The effect of TLR3 priming conditions on MSC immunosuppressive properties

The effect of TLR3 priming conditions on MSC immunosuppressive properties

Abstract Background Mesenchymal stromal cells (MSCs) have regenerative and immunomodulatory properties, making them suitable for cell therapy. Toll-like receptors (TLRs) in MSCs respond to viral load by secreting immunosuppressive or proinflammatory molecules. The expression of anti-inflammatory mol...

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Bibliographic Details
Main Authors: Tatiana Tolstova, Ekaterina Dotsenko, Peter Kozhin, Svetlana Novikova, Victor Zgoda, Alexander Rusanov, Nataliya Luzgina
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Stem Cell Research & Therapy
Subjects:
MSCs
Toll-like receptors
TLR3
Poly(I:C)
Immunosuppression
Jurkat
Online Access:https://doi.org/10.1186/s13287-023-03579-y

Internet

https://doi.org/10.1186/s13287-023-03579-y

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