Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions.

Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions.

Fragile X syndrome, the leading heritable form of intellectual disability, is caused by hypermethylation and transcriptional silencing of large (CGG) repeat expansions (> 200 repeats) in the 5' untranslated region of the fragile X mental retardation 1 (FMR1) gene. As a consequence of FMR1 ge...

Full description

Bibliographic Details
Main Authors: Kyoungmi Kim, David Hessl, Jamie L Randol, Glenda M Espinal, Andrea Schneider, Dragana Protic, Elber Yuksel Aydin, Randi J Hagerman, Paul J Hagerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226811&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226811&type=printable

Similar Items