Cerebral Ischemia Increases Small Ubiquitin-Like Modifier Conjugation within Human Penumbral Tissue: Radiological–Pathological Correlation

Cerebral Ischemia Increases Small Ubiquitin-Like Modifier Conjugation within Human Penumbral Tissue: Radiological–Pathological Correlation

Posttranslational modification by small ubiquitin-like modifier (SUMO) regulates myriad physiological processes within cells and has been demonstrated to be highly activated in murine brains after cerebral ischemia. Numerous in vitro and murine in vivo studies have demonstrated that this increased S...

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Bibliographic Details
Main Authors: Joshua D. Bernstock, Daniel G. Ye, Allison Griffin, Yang-ja Lee, John Lynch, Lawrence L. Latour, Gregory K. Friedman, Dragan Maric, John M. Hallenbeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Neurology
Subjects:
SUMOylation
ischemic stroke
neuroprotection
magnetic resonance imaging
penumbra
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2017.00738/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2017.00738/full

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