Signal enrichment with strain-level resolution in metagenomes using topological data analysis

Signal enrichment with strain-level resolution in metagenomes using topological data analysis

Abstract Background A metagenome is a collection of genomes, usually in a micro-environment, and sequencing a metagenomic sample en masse is a powerful means for investigating the community of the constituent microorganisms. One of the challenges is in distinguishing between similar organisms due to...

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Bibliographic Details
Main Authors: Aldo Guzmán-Sáenz, Niina Haiminen, Saugata Basu, Laxmi Parida
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Genomics
Subjects:
Metagenomics
Topological data analysis
Multi-mapping reads
False positives
Online Access:http://link.springer.com/article/10.1186/s12864-019-5490-y

Internet

http://link.springer.com/article/10.1186/s12864-019-5490-y

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