Efficacy and safety of a 4-year combination therapy of growth hormone and gonadotropin-releasing hormone analogue in pubertal girls with short predicted adult height

Efficacy and safety of a 4-year combination therapy of growth hormone and gonadotropin-releasing hormone analogue in pubertal girls with short predicted adult height

ObjectivesTo improve adult height in pubertal girls with a poor height prediction, treatment with growth hormone (GH) can be used in combination with a gonadotropin releasing hormone agonist (GnRHa), to delay closure of the growth plates. However, there are few studies to support this practice, and...

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Bibliographic Details
Main Authors: Hilde Dotremont, Annick France, Claudine Heinrichs, Sylvie Tenoutasse, Cécile Brachet, Martine Cools, Kathleen De Waele, Guy Massa, Marie-Christine Lebrethon, Inge Gies, Jesse Van Besien, Christine Derycke, Mathieu Ziraldo, Jean De Schepper, Véronique Beauloye, Stijn Verhulst, Raoul Rooman, Marieke den Brinker
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
short stature children
girls
growth hormone treatment (GH)
gonadotropin-releasing hormone agonist (GnRHa)
adult height
puberty
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1113750/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1113750/full

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