A T-Cell Surface Marker Panel Predicts Murine Acute Graft-Versus-Host Disease

A T-Cell Surface Marker Panel Predicts Murine Acute Graft-Versus-Host Disease

Acute graft-versus-host disease (aGvHD) is a severe and often life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT). AGvHD is mediated by alloreactive donor T-cells targeting predominantly the gastrointestinal tract, liver, and skin. Recent work in mice and patien...

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Bibliographic Details
Main Authors: Carina A. Bäuerlein, Musga Qureischi, Zeinab Mokhtari, Paula Tabares, Christian Brede, Ana-Laura Jordán Garrote, Simone S. Riedel, Martin Chopra, Simone Reu, Anja Mottok, Estibaliz Arellano-Viera, Carolin Graf, Miriam Kurzwart, Katharina Schmiedgen, Hermann Einsele, Matthias Wölfl, Paul-Gerhardt Schlegel, Andreas Beilhack
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
acute graft-versus-host disease
alloreactive T cells
transplantation
prediction
mouse models
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.593321/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.593321/full

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