Origins of the tumor microenvironment: quantitative assessment of adipose-derived and bone marrow-derived stroma.

To meet the requirements for rapid tumor growth, a complex array of non-neoplastic cells are recruited to the tumor microenvironment. These cells facilitate tumor development by providing matrices, cytokines, growth factors, as well as vascular networks for nutrient and waste exchange, however their...

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Bibliographic Details
Main Authors: Shannon Kidd, Erika Spaeth, Keri Watson, Jared Burks, Hongbo Lu, Ann Klopp, Michael Andreeff, Frank C Marini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282707?pdf=render