The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester

The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester

Abstract Background Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth the adrenals are essential for neonate salt retention through secretion of aldosterone, while adequate glucocorticoids are r...

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Bibliographic Details
Main Authors: Zoe C. Johnston, Michelle Bellingham, Panagiotis Filis, Ugo Soffientini, Denise Hough, Siladitya Bhattacharya, Marc Simard, Geoffrey L. Hammond, Peter King, Peter J. O’Shaughnessy, Paul A. Fowler
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Medicine
Subjects:
Human
Adrenal
Fetus
Steroid
Maternal smoking
Online Access:http://link.springer.com/article/10.1186/s12916-018-1009-7

Internet

http://link.springer.com/article/10.1186/s12916-018-1009-7

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