Incorporating methylation genome information improves prediction accuracy for drug treatment responses

Incorporating methylation genome information improves prediction accuracy for drug treatment responses

Abstract Background An accumulation of evidence has revealed the important role of epigenetic factors in explaining the etiopathogenesis of human diseases. Several empirical studies have successfully incorporated methylation data into models for disease prediction. However, it is still a challenge t...

Full description

Bibliographic Details
Main Authors: Xiaoxuan Xia, Haoyi Weng, Ruoting Men, Rui Sun, Benny Chung Ying Zee, Ka Chun Chong, Maggie Haitian Wang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Genetics
Subjects:
Methylation
Prediction
SNPs
Neural network
Treatment responses
Online Access:http://link.springer.com/article/10.1186/s12863-018-0644-5

Internet

http://link.springer.com/article/10.1186/s12863-018-0644-5

Similar Items