Telacebec Interferes with Virulence Lipid Biosynthesis Protein Expression and Sensitizes to Other Antibiotics

Telacebec Interferes with Virulence Lipid Biosynthesis Protein Expression and Sensitizes to Other Antibiotics

Tuberculosis (TB), caused by <i>Mycobacterium tuberculosis</i> (Mtb), remains a public health issue, particularly due to multi-drug-resistant Mtb. The bacillus is wrapped in a waxy envelope containing lipids acting as essential virulence factors, accounting for the natural antibiotic res...

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Bibliographic Details
Main Authors: Zhiyu Zhou, Ruddy Wattiez, Patricia Constant, Hedia Marrakchi, Karine Soetaert, Vanessa Mathys, Véronique Fontaine, Sheng Zeng
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Microorganisms
Subjects:
<i>Mycobacterium bovis</i> BCG
telacebec
vancomycin
PDIMs
virulence lipids
Online Access:https://www.mdpi.com/2076-2607/11/10/2469

Internet

https://www.mdpi.com/2076-2607/11/10/2469

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