Stage-specific roles of FGF2 signaling in human neural development

Stage-specific roles of FGF2 signaling in human neural development

This study elucidated the stage-specific roles of FGF2 signaling during neural development using in-vitro human embryonic stem cell-based developmental modeling. We found that the dysregulation of FGF2 signaling prior to the onset of neural induction resulted in the malformation of neural rosettes (...

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Bibliographic Details
Main Authors: Marta Grabiec, Hana Hříbková, Miroslav Vařecha, Dana Střítecká, Aleš Hampl, Petr Dvořák, Yuh-Man Sun
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Stem Cell Research
Subjects:
Neural developmental modeling
Embryonic stem cells
Neural fate
Neurogenesis
FGF2 signaling
Neural stem cell niche
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116301118

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http://www.sciencedirect.com/science/article/pii/S1873506116301118

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