FOXA1 mutations in hormone dependent cancers

The forkhead protein, FOXA1, is a critical interacting partner of the nuclear hormone receptors, oestrogen receptor-α (ER) and androgen receptor (AR), which are major drivers of the two most common cancers, namely breast and prostate cancer. Over the past few years, progress has been made in our und...

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Bibliographic Details
Main Authors: Jessica Louise Louvain Robinson, Kelly A Holmes, Jason S Carroll
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00020/full