Eradication of intracellular <it>Francisella tularensis </it>in THP-1 human macrophages with a novel autophagy inducing agent

<p>Abstract</p> <p>Background</p> <p>Autophagy has been shown recently to play an important role in the intracellular survival of several pathogenic bacteria. In this study, we investigated the effect of a novel small-molecule autophagy-inducing agent, AR-12, on the sur...

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Bibliographic Details
Main Authors: Gunn John S, Wang Dasheng, Curry Heather, Kulp Samuel K, Soni Shilpa, Chiu Hao-Chieh, Schlesinger Larry S, Chen Ching-Shih
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/110