Preclinical evaluations of Pfs25-EPA and Pfs230D1-EPA in AS01 for a vaccine to reduce malaria transmission

Preclinical evaluations of Pfs25-EPA and Pfs230D1-EPA in AS01 for a vaccine to reduce malaria transmission

Summary: Malaria transmission-blocking vaccine candidates Pfs25-EPA and Pfs230D1-EPA target sexual stage development of Plasmodium falciparum parasites in the mosquito host, thereby reducing mosquito infectivity. When formulated on Alhydrogel, Pfs25-EPA has demonstrated safety and immunogenicity in...

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Bibliographic Details
Main Authors: Kelly M. Rausch, Emma K. Barnafo, Lynn E. Lambert, Olga Muratova, J. Patrick Gorres, Charles Anderson, David L. Narum, Yimin Wu, Robert D. Morrison, Irfan Zaidi, Patrick E. Duffy
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Parasitology
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012695

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http://www.sciencedirect.com/science/article/pii/S2589004223012695

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