Cleavage-embryo genes and transposable elements are regulated by histone variant H2A.X

During mammalian preimplantation development, stimulation of zygotic genome activation (ZGA) and transposable elements (TEs) shapes totipotency profiling. A rare mouse embryonic stem cells (mESCs) subpopulation is capable of transiently entering a state resembling 2-cell stage embryos, with subtypes...

Full description

Bibliographic Details
Main Authors: Kai-yi SUN, Shi-meng GUO, Gui-ping CHENG, Ying YIN, Ximiao HE, Li-quan ZHOU
Format: Article
Language:English
Published: The Society for Reproduction and Development 2021-08-01
Series:The Journal of Reproduction and Development
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jrd/67/5/67_2021-065/_pdf/-char/en