The Effect of Vincristine on Hypoxic, Apoptotic, and Autophagic Gene Expressions in Gastric Cancer Cells under Hypoxic Conditions

Background: Apoptosis and autophagy functions are known as death-inducing mechanisms. Vincristine (VCR) is a chemotherapeutic drug that binds with tubulin dimers and induces apoptosis in cancer cells. Furthermore, VCR protects cancer cells from apoptosis, allowing them to enter autophagy. This makes...

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Bibliographic Details
Main Authors: Meliha Irmak-Yazicioglu, Betül Ceylaner
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-07-01
Series:Middle East Journal of Cancer
Subjects:
Online Access:https://mejc.sums.ac.ir/article_49058_11486fc4b66b3887784ad9637a457d41.pdf