Prognostic value of absolute quantification of mutated KRAS in circulating tumour DNA in lung adenocarcinoma patients prior to therapy

Prognostic value of absolute quantification of mutated KRAS in circulating tumour DNA in lung adenocarcinoma patients prior to therapy

Abstract Droplet digital polymerase chain reaction (ddPCR) is a highly sensitive and accurate method for quantification of nucleic acid sequences. We used absolute quantification of mutated v‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homology gene (KRAS) by ddPCR to investigate the prognostic role...

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Bibliographic Details
Main Authors: Sissel Gyrid Freim Wahl, Hong Yan Dai, Elisabeth F Emdal, Anine L Ottestad, Vibeke G Dale, Elin Richardsen, Tarje O Halvorsen, Bjørn Henning Grønberg
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:The Journal of Pathology: Clinical Research
Subjects:
non‐small cell lung cancer
liquid biopsy
plasma analyses
droplet digital PCR
ctDNA levels
Online Access:https://doi.org/10.1002/cjp2.200

Internet

https://doi.org/10.1002/cjp2.200

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