Late domain dependent E-cadherin recruitment into extracellular vesicles

E-cadherin, a transmembrane protein involved in epithelial cell-cell adhesion and signaling, is found in exosomal fractions isolated from human body fluids. A cellular mechanism for recruitment of E-cadherin into extracellular vesicles (EVs) has not yet been defined. Here, we show that E-cadherin is...

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Bibliographic Details
Main Authors: Sebastian Bänfer, Sophie Kutscher, Fenja Fleck, Martina Dienst, Christian Preußer, Elke Pogge von Strandmann, Ralf Jacob
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.878620/full