Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment

Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment

Introduction: Therapeutic agents that target complement are increasingly available for glomerular diseases. However, the mechanisms linking glomerular complement deposition with inflammation and damage are incompletely understood. Complement factor H–related protein 5 (FHR5) interacts with complemen...

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Bibliographic Details
Main Authors: Nicholas R. Medjeral-Thomas, Hilary Moffitt, Hannah J. Lomax-Browne, Nicholas Constantinou, Tom Cairns, H. Terence Cook, Matthew C. Pickering
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Kidney International Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024919313865

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http://www.sciencedirect.com/science/article/pii/S2468024919313865

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