Production of p-amino-l-phenylalanine (l-PAPA) from glycerol by metabolic grafting of Escherichia coli

Production of p-amino-l-phenylalanine (l-PAPA) from glycerol by metabolic grafting of Escherichia coli

Abstract Background The non-proteinogenic aromatic amino acid, p-amino-l-phenylalanine (l-PAPA) is a high-value product with a broad field of applications. In nature, l-PAPA occurs as an intermediate of the chloramphenicol biosynthesis pathway in Streptomyces venezuelae. Here we demonstrate that the...

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Bibliographic Details
Main Authors: Behrouz Mohammadi Nargesi, Natalie Trachtmann, Georg A. Sprenger, Jung-Won Youn
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Microbial Cell Factories
Subjects:
Escherichia coli
Non-proteinogenic aromatic amino acids
p-Amino-l-phenylalanine
Metabolic grafting
Online Access:http://link.springer.com/article/10.1186/s12934-018-0996-6

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http://link.springer.com/article/10.1186/s12934-018-0996-6

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