Primary and hTERT-Transduced Mesothelioma-Associated Fibroblasts but Not Primary or hTERT-Transduced Mesothelial Cells Stimulate Growth of Human Mesothelioma Cells

Primary and hTERT-Transduced Mesothelioma-Associated Fibroblasts but Not Primary or hTERT-Transduced Mesothelial Cells Stimulate Growth of Human Mesothelioma Cells

Pleural mesothelioma (PM) is an aggressive malignancy that develops in a unique tumor microenvironment (TME). However, cell models for studying the TME in PM are still limited. Here, we have generated and characterized novel human telomerase reverse transcriptase (hTERT)-transduced mesothelial cell...

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Bibliographic Details
Main Authors: Alexander Ries, Astrid Slany, Christine Pirker, Johanna C. Mader, Doris Mejri, Thomas Mohr, Karin Schelch, Daniela Flehberger, Nadine Maach, Muhammad Hashim, Mir Alireza Hoda, Balazs Dome, Georg Krupitza, Walter Berger, Christopher Gerner, Klaus Holzmann, Michael Grusch
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
pleural mesothelioma
pleural mesothelial cells
mesothelioma-associated fibroblasts
tumor microenvironment
conditioned medium
human telomerase reverse transcriptase
Online Access:https://www.mdpi.com/2073-4409/12/15/2006

Internet

https://www.mdpi.com/2073-4409/12/15/2006

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