Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential

Summary: Ureteric bud (UB) is the embryonic kidney progenitor tissue that gives rise to the collecting duct and lower urinary tract. UB-like structures generated from human pluripotent stem cells by previously reported methods show limited developmental ability and limited branching. Here we report...

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Bibliographic Details
Main Authors: Shin-Ichi Mae, Makoto Ryosaka, Satoko Sakamoto, Kyoko Matsuse, Aya Nozaki, Maiko Igami, Ryotaro Kabai, Akira Watanabe, Kenji Osafune
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472030944X