Pyruvate dehydrogenase kinase regulates macrophage polarization in metabolic and inflammatory diseases

Macrophages are highly heterogeneous and plastic, and have two main polarized phenotypes that are determined by their microenvironment, namely pro- and anti-inflammatory macrophages. Activation of pro-inflammatory macrophages is closely associated with metabolic reprogramming, especially that of aer...

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Príomhchruthaitheoirí: Chenyu Li, Chuanbin Liu, Junfeng Zhang, Yanyu Lu, Bingtong Jiang, Huabao Xiong, Chunxia Li
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Frontiers Media S.A. 2023-12-01
Sraith:Frontiers in Immunology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1296687/full