Unmasking the biological function and regulatory mechanism of NOC2L: a novel inhibitor of histone acetyltransferase
Abstract NOC2 like nucleolar associated transcriptional repressor (NOC2L) was recently identified as a novel inhibitor of histone acetyltransferase (INHAT). NOC2L is found to have two INHAT function domains and regulates histone acetylation in a histone deacetylases (HDAC) independent manner, which...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-023-03877-2 |