The angiotensin II type 1 receptor C-terminal Lys residues interact with tubulin and modulate receptor export trafficking.

The physiological and pathological functions of angiotensin II are largely mediated through activating the cell surface angiotensin II type 1 receptor (AT1R). However, the molecular mechanisms underlying the transport of newly synthesized AT1R from the endoplasmic reticulum (ER) to the cell surface...

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Bibliographic Details
Main Authors: Xiaoping Zhang, Hong Wang, Matthew T Duvernay, Shu Zhu, Guangyu Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3581488?pdf=render