Depletion of muscularis macrophages ameliorates inflammation-driven dysmotility in murine colitis model

Abstract Previously, the presence of a blood-myenteric plexus barrier and its disruption was reported in experimentally induced colitis via a macrophage-dependent process. The aim of this study is to reveal how myenteric barrier disruption and subsequent neuronal injury affects gut motility in vivo...

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Bibliographic Details
Main Authors: Szilamér Ferenczi, Fruzsina Mogor, Peter Takacs, Tamas Kovacs, Viktoria E. Toth, Zoltán V. Varga, Krisztina Kovács, Zoltan Lohinai, Koppány Csaba Vass, Nandor Nagy, David Dora
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50059-7