Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function

Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function

Embryonic taste bud primordia are specified as taste placodes on the tongue surface and differentiate into the first taste receptor cells (TRCs) at birth. Throughout adult life, TRCs are continually regenerated from epithelial progenitors. Sonic hedgehog (SHH) signaling regulates TRC development and...

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Bibliographic Details
Main Authors: Erin J Golden, Eric D Larson, Lauren A Shechtman, G Devon Trahan, Dany Gaillard, Timothy J Fellin, Jennifer K Scott, Kenneth L Jones, Linda A Barlow
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
taste
Hedgehog signaling
regeneration
SOX2
taste bud
RNAseq
Online Access:https://elifesciences.org/articles/64013

Internet

https://elifesciences.org/articles/64013

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