CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage

CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage

Aging is a major risk factor of osteoarthritis, which is characterized by the degeneration of articular cartilage. CCN3, a member of the CCN family, is expressed in cartilage and has various physiological functions during chondrocyte development, differentiation, and regeneration. Here, we examine t...

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Bibliographic Details
Main Authors: Miho Kuwahara, Koichi Kadoya, Sei Kondo, Shanqi Fu, Yoshiko Miyake, Ayako Ogo, Mitsuaki Ono, Takayuki Furumatsu, Eiji Nakata, Takako Sasaki, Shogo Minagi, Masaharu Takigawa, Satoshi Kubota, Takako Hattori
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
cellular communication network factor 3
CCN3
NOV
primary chondrocytes
aging
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/21/20/7556

Internet

https://www.mdpi.com/1422-0067/21/20/7556

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