Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate

Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate

Abstract The exponential rise in molecular and genomic data has generated a vast array of therapeutic targets. Oligonucleotide-based technologies to down regulate these molecular targets have promising therapeutic efficacy. However, there is relatively limited success in translating this into effect...

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Bibliographic Details
Main Authors: Noriko Satake, Connie Duong, Sakiko Yoshida, Michael Oestergaard, Cathy Chen, Rachael Peralta, Shuling Guo, Punit P Seth, Yueju Li, Laurel Beckett, Jong Chung, Jan Nolta, Nitin Nitin, Joseph M Tuscano
Format: Article
Language:English
Published: BMC 2016-07-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2015.00210

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http://link.springer.com/article/10.2119/molmed.2015.00210

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