Glycation Leads to Increased Invasion of Glioblastoma Cells

Glioblastoma (GBM) is a highly aggressive and invasive brain tumor with a poor prognosis despite extensive treatment. The switch to aerobic glycolysis, known as the Warburg effect, in cancer cells leads to an increased production of methylglyoxal (MGO), a potent glycation agent with pro-tumorigenic...

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Bibliographic Details
Main Authors: Paola Schildhauer, Philipp Selke, Christian Scheller, Christian Strauss, Rüdiger Horstkorte, Sandra Leisz, Maximilian Scheer
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/9/1219