Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells [version 2; peer review: 2 approved]
Background: Resolving causal genes for type 2 diabetes at loci implicated by genome-wide association studies (GWAS) requires integrating functional genomic data from relevant cell types. Chromatin features in endocrine cells of the pancreatic islet are particularly informative and recent studies lev...
Main Authors: | Jason M. Torres, Vibe Nylander, Han Sun, Martijn van de Bunt, Damien J. Downes, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2023-08-01
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Series: | Wellcome Open Research |
Subjects: | |
Online Access: | https://wellcomeopenresearch.org/articles/8-165/v2 |
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