Patient-Derived Non-Muscular Invasive Bladder Cancer Xenografts of Main Molecular Subtypes of the Tumor for Anti-Pd-l1 Treatment Assessment

Patient-Derived Non-Muscular Invasive Bladder Cancer Xenografts of Main Molecular Subtypes of the Tumor for Anti-Pd-l1 Treatment Assessment

Background: Establishment of heterotopic patient-derived xenografts of primary and relapsed non-muscular invasive bladder cancer (NMIBC) to explore the biological property of PD-L1 signaling that may impact bladder tumor growth in humanized animals. Methods: Tumor cells of luminal, basal, and p53 su...

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Bibliographic Details
Main Authors: Ekaterina Blinova, Dmitry Roshchin, Evgenya Kogan, Elena Samishina, Tatiana Demura, Olga Deryabina, Irina Suslova, Dmitry Blinov, Pavel Zhdanov, Usif Osmanov, Mikhail Nelipa, Andrey Kaprin
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
non-muscular invasive bladder cancer
patient-derived xenograft
anti-PD-L1 treatment
metastasis
molecular subtypes
Online Access:https://www.mdpi.com/2073-4409/8/6/526

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https://www.mdpi.com/2073-4409/8/6/526

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