Rolling circle transcription of ribozymes from promoterless single-stranded DNA nanocircles in mammalian cells [Ribozimlerin, promotorsuz tek-iplikli DNA çemberlerinin rolling circle transkripsiyonu ile memeli hücrelerinde üretimi]
Self-processing hairpin ribozymes have been synthesized from promoterless singlestranded DNA circles (73 nt) within mammalian cells. Following lipid-mediated transient transfection, DNA circles were efficiently internalized by mouse L cells (OST7–1) that stably express T7 RNA polymerase confining...
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| Format: | Article |
| Language: | English |
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De Gruyter
2006-03-01
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| Series: | Türk Biyokimya Dergisi |
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| Online Access: | http://www.turkjbiochem.com/2006/002_012.pdf |