Towards medical imaging of drug photoactivation: Development of light responsive magnetic resonance imaging and chemical exchange saturation transfer contrast agents

Abstract In recent years, the use of light to selectively and precisely activate drugs has been developed along the fundamental concepts of photopharmacology. One of the key methods in this field relies on transiently silencing the drug activity with photocleavable protecting groups (PPGs). To effec...

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Bibliographic Details
Main Authors: Ilse M. Welleman, Carlijn L. F. vanBeek, Ioana Belcin, Albert M. Schulte, Rudi A. J. O. Dierckx, Ben L. Feringa, Hendrikus H. Boersma, Wiktor Szymański
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Smart Molecules
Subjects:
Online Access:https://doi.org/10.1002/smo.20230029