Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents

Arylalkane-derived prodrugs of arylacetic acids are a small group of substances that have long been known for their anti-inflammatory action. Despite their ease of synthesis and good potential for the development of new potent and safe anti-inflammatory agents, this group of substances has not recei...

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Bibliographic Details
Main Authors: Maria Antonietta Occhiuzzi, Giuseppina Ioele, Michele De Luca, Bruno Rizzuti, Domenica Scordamaglia, Rosamaria Lappano, Marcello Maggiolini, Antonio Garofalo, Fedora Grande
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/25/1/435