Transcriptional, Epigenetic and Pharmacological Control of JAK/STAT Pathway in NK Cells

Transcriptional, Epigenetic and Pharmacological Control of JAK/STAT Pathway in NK Cells

Differentiation of Natural Killer (NK) cells is a stepwise process having its origin in the bone marrow and proceeding in the periphery, where these cells follow organ specific trajectories. Several soluble factors and cytokines regulate the distinct stages of NK cell differentiation, and ultimately...

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Bibliographic Details
Main Authors: Gianluca Scarno, Giuseppe Pietropaolo, Chiara Di Censo, Massimo Gadina, Angela Santoni, Giuseppe Sciumè
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
NK cells
innate lymphoid cells
JAK
STAT
cytokine
transcriptome
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02456/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02456/full

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