DNA Methylation and RNA-DNA Hybrids Regulate the Single-Molecule Localization of a DNA Methyltransferase on the Bacterial Nucleoid

DNA Methylation and RNA-DNA Hybrids Regulate the Single-Molecule Localization of a DNA Methyltransferase on the Bacterial Nucleoid

ABSTRACT Bacterial DNA methyltransferases (MTases) function in restriction modification systems, cell cycle control, and the regulation of gene expression. DnmA is a recently described DNA MTase that forms N6-methyladenosine at nonpalindromic 5′-GACGAG-3′ sites in Bacillus subtilis, yet how DnmA act...

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Bibliographic Details
Main Authors: Nicolas L. Fernandez, Ziyuan Chen, David E. H. Fuller, Lieke A. van Gijtenbeek, Taylor M. Nye, Julie S. Biteen, Lyle A. Simmons
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:mBio
Subjects:
replisome
epigenetic
superresolution microscopy
Bacillus subtilis
restriction modification
Online Access:https://journals.asm.org/doi/10.1128/mbio.03185-22

Internet

https://journals.asm.org/doi/10.1128/mbio.03185-22

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