Self-assembled ferritin nanoparticles displaying PcrV and OprI as an adjuvant-free Pseudomonas aeruginosa vaccine

Self-assembled ferritin nanoparticles displaying PcrV and OprI as an adjuvant-free Pseudomonas aeruginosa vaccine

IntroductionSerious infections of Pseudomonas aeruginosa (PA) in hospitals and the emergence and increase of multidrug resistance have raised an urgent need for effective vaccines. However, no vaccine has been approved to date. One possible reason for this is the limited immune response due to the l...

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Bibliographic Details
Main Authors: Yuhang Li, Ruixue Pu, Yi Zhang, Yiwen Zhang, Yujie Wei, Sheng Zeng, Chen Gao, Ying Wang, Daijiajia Yin, Yueyue Zhang, Jiqing Wan, Quanming Zou, Jiang Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
ferritin nanoparticles
adjuvant-free
Pseudomonas aeruginosa
PcrV
OprI
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1184863/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1184863/full

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