A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding

Ischaemia-reperfusion (IR) injury is the paradoxical consequence of the rapid restoration of blood flow to an ischaemic organ. Although reperfusion is essential for tissue survival in conditions such as myocardial infarction and stroke, the excessive production of mitochondrial reactive oxygen speci...

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Библиографические подробности
Главные авторы: Annabel Sorby-Adams, Tracy A. Prime, Jan Lj Miljkovic, Hiran A. Prag, Thomas Krieg, Michael P. Murphy
Формат: Статья
Язык:English
Опубликовано: Elsevier 2024-06-01
Серии:Redox Biology
Предметы:
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S221323172400137X