Human cutaneous neurofibroma matrisome revealed by single-cell RNA sequencing

Abstract Neurofibromatosis Type I (NF1) is a neurocutaneous genetic syndrome characterized by a wide spectrum of clinical presentations, including benign peripheral nerve sheath tumor called neurofibroma. These tumors originate from the Schwann cell lineage but other cell types as well as extracellu...

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Bibliographic Details
Main Authors: Jean-Philippe Brosseau, Adwait A. Sathe, Yong Wang, Toan Nguyen, Donald A. Glass, Chao Xing, Lu Q. Le
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Acta Neuropathologica Communications
Online Access:https://doi.org/10.1186/s40478-020-01103-4