2349 The role of interleukin-23 in human melanoma
OBJECTIVES/SPECIFIC AIMS: Interleukin-23 (IL-23) promotes differentiation of naïve T-cells into Th17 cells, which drive the pathogenesis of autoinflammatory conditions such as psoriasis. IL-23-neutralizing antibody therapies are now in use for treatment of psoriasis, with promising results. Studies...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2018-06-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866118001358/type/journal_article |