2349 The role of interleukin-23 in human melanoma

OBJECTIVES/SPECIFIC AIMS: Interleukin-23 (IL-23) promotes differentiation of naïve T-cells into Th17 cells, which drive the pathogenesis of autoinflammatory conditions such as psoriasis. IL-23-neutralizing antibody therapies are now in use for treatment of psoriasis, with promising results. Studies...

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Bibliographic Details
Main Authors: Aditi Jani, Sandeep Chaudhary, Zorica Janjetovic, Mohammad A. Sherwani, Nabiha Yusuf, Andrzej Slominski, Mohammad Athar, Craig Elmets
Format: Article
Language:English
Published: Cambridge University Press 2018-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866118001358/type/journal_article