Could Aspirin and Diets High in Fiber Act Synergistically to Reduce the Risk of Colon Cancer in Humans?

Could Aspirin and Diets High in Fiber Act Synergistically to Reduce the Risk of Colon Cancer in Humans?

Early inhibition of inflammation suppresses the carcinogenic process. Aspirin is the most commonly used non-steroid anti-inflammatory drugs (NSAIDs), and it irreversibly inhibits cyclooxygenase-1 and -2 (COX1, COX2). Multiple randomized clinical trials have demonstrated that aspirin offers substanti...

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Bibliographic Details
Main Authors: Pan Pan, Yi-Wen Huang, Kiyoko Oshima, Martha Yearsley, Jianying Zhang, Jianhua Yu, Mark Arnold, Li-Shu Wang
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
human clinical trials
aspirin
salicylic acid
cyclooxygenase 2
fruits and vegetables
phytochemicals
synergy
bell/U-shaped
cancer prevention
Online Access:http://www.mdpi.com/1422-0067/19/1/166

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http://www.mdpi.com/1422-0067/19/1/166

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