Automated Radiosynthesis of [<sup>18</sup>F]FluoFAPI and Its Dosimetry and Single Acute Dose Toxicological Evaluation

Background: Cancer-associated fibroblasts have become a new target for therapy. Fibroblasts present within malignancies express the fibroblast activation protein (FAP). Inhibitors to FAP (FAPI) are small molecules recently developed as a theranostic agents for imaging and radiotherapy. All currently...

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Bibliografische gegevens
Hoofdauteurs: Jason A. Witek, Allen F. Brooks, Sahil M. Kapila, Wade P. Winton, Jenelle R. Stauff, Peter J. H. Scott, Benjamin L. Viglianti
Formaat: Artikel
Taal:English
Gepubliceerd in: MDPI AG 2024-06-01
Reeks:Pharmaceuticals
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Online toegang:https://www.mdpi.com/1424-8247/17/7/833