Large Granular Lymphocytic Leukemia: Clinical Features, Molecular Pathogenesis, Diagnosis and Treatment

Large Granular Lymphocytic Leukemia: Clinical Features, Molecular Pathogenesis, Diagnosis and Treatment

Large granular lymphocytic (LGL) leukemia is a lymphoproliferative disorder characterized by persistent clonal expansion of mature T- or natural killer cells in the blood via chronic antigenic stimulation. LGL leukemia is associated with specific immunophenotypic and molecular features, particularly...

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Bibliographic Details
Main Authors: Fauzia Ullah, Mariam Markouli, Mark Orland, Olisaemeka Ogbue, Danai Dima, Najiullah Omar, Moaath K. Mustafa Ali
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cancers
Subjects:
large granular lymphocytic leukemia
molecular pathogenesis
natural killer LGL leukemia
STAT3
targeted therapies
Online Access:https://www.mdpi.com/2072-6694/16/7/1307

Internet

https://www.mdpi.com/2072-6694/16/7/1307

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