Conditionally Replicating Vectors Mobilize Chimeric Antigen Receptors against HIV

Conditionally Replicating Vectors Mobilize Chimeric Antigen Receptors against HIV

Human immunodeficiency virus (HIV) is an attractive target for chimeric antigen receptor (CAR) therapy. CAR T cells have proved remarkably potent in targeted killing of cancer cells, and we surmised that CAR T cells could prove useful in eradicating HIV-infected cells. Toward this goal, we interroga...

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Bibliographic Details
Main Authors: Ryan Z. Urak, Citradewi Soemardy, Roslyn Ray, Shirley Li, Galina Shevchenko, Tristan Scott, Laura Lim, Xiuli Wang, Kevin V. Morris
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
HIV
CAR T-cell
45-46
Conditionally replicating vectors
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120301996

Internet

http://www.sciencedirect.com/science/article/pii/S2329050120301996

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