Prioritization and functional assessment of noncoding variants associated with complex diseases

Prioritization and functional assessment of noncoding variants associated with complex diseases

Abstract Unraveling functional noncoding variants associated with complex diseases is still a great challenge. We present a novel algorithm, Prioritization And Functional Assessment (PAFA), that prioritizes and assesses the functionality of genetic variants by introducing population differentiation...

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Bibliographic Details
Main Authors: Lin Zhou, Fangqing Zhao
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Genome Medicine
Subjects:
Complex disease
Functional annotation
Genetic variant
Variant prioritization
Noncoding variant
Online Access:http://link.springer.com/article/10.1186/s13073-018-0565-y

Internet

http://link.springer.com/article/10.1186/s13073-018-0565-y

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