Identification of anti-tumor constituents from toad skin and toad venom by UPLC-QTOF/MS in-depth chemical profiling combined with bioactivity-based molecular networking

Identification of anti-tumor constituents from toad skin and toad venom by UPLC-QTOF/MS in-depth chemical profiling combined with bioactivity-based molecular networking

Toad skin (TS) and toad venom (TV) are two different traditional Chinese medicine (TCM) prepared from Bufo bufo gargarizans Cantor and Bufo melanostictus Schneider. Both of them were used in the treatment of ulcers, and now they are regarded as animal drugs with anti-tumor activity. However, the com...

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Bibliographic Details
Main Authors: Ruxia Liu, Yuhao Zhang, Ruijing Zhang, Huawu Zeng, Yunheng Shen, Xu Li, Chi Ma, Fan Huang, Lulu Wang, Renwen Zhu, Xike Xu, Weidong Zhang, Ji Ye
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Arabian Journal of Chemistry
Subjects:
Toad skin
Toad venom
UPLC-QTOF/MS
Molecular networking
Anti-tumor activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223008894

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http://www.sciencedirect.com/science/article/pii/S1878535223008894

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