Exploring the Impact of Cleavage and Polyadenylation Factors on Pre-mRNA Splicing Across Eukaryotes
In human, mouse, and Drosophila, the spliceosomal complex U1 snRNP (U1) protects transcripts from premature cleavage and polyadenylation at proximal intronic polyadenylation signals (PAS). These U1-mediated effects preserve transcription integrity, and are known as telescripting. The watchtower role...
| Հիմնական հեղինակներ: | , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Oxford University Press
2017-07-01
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| Շարք: | G3: Genes, Genomes, Genetics |
| Խորագրեր: | |
| Առցանց հասանելիություն: | http://g3journal.org/lookup/doi/10.1534/g3.117.041483 |