Exploring the Impact of Cleavage and Polyadenylation Factors on Pre-mRNA Splicing Across Eukaryotes
In human, mouse, and Drosophila, the spliceosomal complex U1 snRNP (U1) protects transcripts from premature cleavage and polyadenylation at proximal intronic polyadenylation signals (PAS). These U1-mediated effects preserve transcription integrity, and are known as telescripting. The watchtower role...
| Main Authors: | , |
|---|---|
| 格式: | Article |
| 語言: | English |
| 出版: |
Oxford University Press
2017-07-01
|
| 叢編: | G3: Genes, Genomes, Genetics |
| 主題: | |
| 在線閱讀: | http://g3journal.org/lookup/doi/10.1534/g3.117.041483 |