In vitro activities of thiazolidione derivatives combined with daptomycin against clinical Enterococcus faecium strains

Abstract Background Previous reports have demonstrated two thiazolidione derivatives (H2-60 and H2-81) can robustly inhibit the planktonic growth and biofilm formation of S. epidermidis and S. aureus by targeting the histidine kinase YycG. Whereas the antibacterial and anti-biofilm activity of these...

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Bibliographic Details
Main Authors: Zhong Chen, Yanpeng Xiong, Yuanyuan Tang, Yuxi Zhao, Junwen Chen, Jinxin Zheng, Yang Wu, Qiwen Deng, Di Qu, Zhijian Yu
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-021-02423-8